Insights into the Antimicrobial Potential of Dithiocarbamate Anions and Metal-Based Species

Bacterial infection remains a worldwide problem that requires urgent addressing. Overuse and poor disposal of antibacterial agents abet the emergence bacterial resistance mechanisms. There is clear need for new approaches development therapeutics. Herein, potential molecules based on dithiocarbamate anions, general formula R(R’)NCS2(−), metal salts transition metals main group elements, summarized. Preclinical studies show broad range potential, these investigations are supported by appraisals possible biological targets mechanisms action to guide chemical syntheses. This bibliographic review literature points exciting dithiocarbamate-based therapeutics in crucial battle against bacteria. Additionally, included this overview, sake completeness, mention far fewer antifungal dithiocarbamates even less work conducted antiparasitic behavior.